Reciprocal MDK–THRB lipid-oxidation transcriptional programs in MASH-associated hepatocellular carcinoma
3 Biotech
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2026 (Vol 16:474)
Authors: V. Muniappan, K. Dwivedi, S. Sakila, J. Sejpal, P. Varadhan, K. Santhosha, S. Ramachandiran, et al.
Research Focus: Two-cohort human transcriptomic study demonstrating reciprocal MDK–THRB regulatory axes and fatty-acid oxidation signatures in liver cancer progression.
Oral Versus Injectable Incretin-Based Anti-Obesity Therapies: An Integrated Computational and Evidence-Based Comparison
OMICS: A Journal of Integrative Biology
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2026
Authors: Lorika Sahu, Laxmipriya Nayak, Aakankshya Tripathy, Sivaramakrishnan Ramachandiran, Baranika Gunasekaran, Tejasri Lokaiah
Research Focus: Computational docking, dynamics, and clinical evidence-based synthesis evaluating orforglipron, semaglutide, and tirzepatide therapeutic mechanisms.
Lipoprotein(a) and premature myocardial infarction: Mechanistic insights and implications for PCI-era residual risk
Int. J. of Cardiology: Cardiovasc Risk Prev
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2026
Authors: Santosh Mohanlal Modani, Shravan Kumar Rampelly, Shafi Palagiri, Samiya Begum Ibrahim, Sivaramakrishnan Ramachandiran
Research Focus: Molecular and clinical implications of genetically determined Lp(a) levels driving residual ischemic risk following percutaneous coronary intervention (PCI).
Structure-Based Prioritization of Metformin-Associated Targets Across Multiple Disease Contexts
In Silico Research in Biomedicine
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2026
Authors: K. Vijayakumar, N. Mathur, D. Das, A. Chaudhary, P. Varadhan, S. K. Mishra, S. Ramachandiran
Research Focus: In silico target mapping across metabolic, oncological, neurodegenerative, reproductive, and aging-inflammatory biological axes.
Integrated computational and machine-learning pipeline for identification of flavonoid-based PIKfyve inhibitors
Next Research
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2026
Authors: A. Chaudhary, V. Solanki, K. K. Goel, S. Thapliyal, D. Yadav, Ishika, S. Ramachandiran
Research Focus: GaMD pharmacophore modeling, ensemble docking, and experimental validation targeting PIKfyve for antiviral and anticancer therapeutics.
Genomic landscape of triple-negative breast cancer in South Asian populations: a systematic review
BMC Cancer
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2026
Authors: S. Bhattacharyya, J. V. Thomas, A. Prasad, A. Deep, FNU Bhuvan, S. Ramachandiran, R. K. Garanayak
Research Focus: Population-specific genomic characteristics, mutation frequencies, and actionable clinical biomarkers in South Asian TNBC cohorts.